BDBM545922 US11286268, Compound 1415

SMILES CN1CCC(C)(CC1)c1ncc2nc(C)n(CCOc3ccc(Cl)cc3-c3ccnc4c(csc34)C(O)=O)c(=O)c2c1C#N

InChI Key InChIKey=KPZJKEFXLXRKTB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 545922   

TargetEukaryotic translation initiation factor 4E-binding protein 1(Human)
Effector Therapeutics

US Patent
LigandPNGBDBM545922(US11286268, Compound 1415)
Affinity DataIC50: 16.8nMAssay Description:eIF4E protein was pre-incubated with EDA-m7GDP-ATTO-550 in FPB at 2xconcentrations for 5 minutes prior to the addition of compounds. Compounds (100x)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent