BDBM547774 (R)-2-(3-(4-Fluorophenoxy)azetidin-1-yl)-4-((tetrahydro-2H-pyran-4-yl)amino)-6,7-dihydrothieno[3,2-d]pyrimidine 5-oxide::US11292799, Example 3
SMILES [O-][S@@+]1CCc2nc(nc(NC3CCOCC3)c12)N1CC(C1)Oc1ccc(F)cc1
InChI Key InChIKey=JVAPDAPCHBQTBT-GDLZYMKVSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 547774
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [538-740](Homo sapiens (Human))
Union Therapeutics
US Patent
Union Therapeutics
US Patent
Affinity DataIC50: <10nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [5380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair