BDBM548531 WO2022093881, Ex-10.40
SMILES C[C@@]1(COC[C@H]1F)N1CCN(CC1)c1cc2cc(NC(=O)[C@H]3C[C@@H](C3)C#N)ncc2cc1Cl
InChI Key InChIKey=YCFSGOJKZRVFCJ-NMNYSWNBSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 548531
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Homo sapiens (Human))
MERCK SHARP & DOHME LLC
WIPO
MERCK SHARP & DOHME LLC
WIPO
Affinity DataIC50: 0.0800nMAssay Description: The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...More data for this Ligand-Target Pair