BDBM548531 WO2022093881, Ex-10.40

SMILES C[C@@]1(COC[C@H]1F)N1CCN(CC1)c1cc2cc(NC(=O)[C@H]3C[C@@H](C3)C#N)ncc2cc1Cl

InChI Key InChIKey=YCFSGOJKZRVFCJ-NMNYSWNBSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 548531   

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Homo sapiens (Human))
MERCK SHARP & DOHME LLC

WIPO
LigandPNGBDBM548531(WO2022093881, Ex-10.40)
Affinity DataIC50:  0.0800nMAssay Description: The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed