BDBM548563 WO2022093881, Ex-10.72
SMILES C[C@H]1[C@H]([C@@H]1c1ccccn1)C(=O)Nc1cc2cc(N3CCN(CC3)[C@@]3(C)COC[C@H]3F)c(Cl)cc2cn1
InChI Key InChIKey=XSKSTEOECMPMTQ-MVODMDEISA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 548563
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Homo sapiens (Human))
Merck Sharp &Amp
WIPO
Merck Sharp &Amp
WIPO
Affinity DataIC50: 0.0800nMAssay Description: The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...More data for this Ligand-Target Pair