BDBM549176 (5R)?N2-methyl-5-oxido-N4-tetrahydropyran-4-yl-N2-(2-tetrahydropyran-4-ylethyl)-6,7-dihydrothieno[3,2-d]pyrimidin-5-ium-2,4-diamine::US11299497, Example 1

SMILES CN(CCC1CCOCC1)c1nc2CC[S@@+]([O-])c2c(NC2CCOCC2)n1

InChI Key InChIKey=LFFRNQOQQGZBKA-HHHXNRCGSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 549176   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741](Homo sapiens (Human))
Union Therapeutics

US Patent
LigandPNGBDBM549176((5R)?N2-methyl-5-oxido-N4-tetrahydropyran-4-yl-N2-...)
Affinity DataIC50:  30nMAssay Description:The human PDE41 Dcatalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent