BDBM549179 (5R)?N2-ethyl-5-oxido-N4-tetrahydropyran-4-yl-N2-(2-tetrahydropyran-4-ylethyl)-6,7-dihydrothieno[3,2-d]pyrimidin-5-ium-2,4-diamine::US11299497, Example 2
SMILES CCN(CCC1CCOCC1)c1nc2CC[S@@+]([O-])c2c(NC2CCOCC2)n1
InChI Key InChIKey=UXCHMVPQIGTLTL-MUUNZHRXSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 549179
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741](Homo sapiens (Human))
Union Therapeutics
US Patent
Union Therapeutics
US Patent
Affinity DataIC50: <10nMAssay Description:The human PDE41 Dcatalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate)...More data for this Ligand-Target Pair