BDBM549297 2-chloro-N- cyclobutyl-5- oxido-6,7-dihydro- thieno[3,2-d]pyrimi- din-5-ium-4-amine::US11299497, Example 12

SMILES CC[C@H](C)Nc1nc(nc2CC[S@@+]([O-])c12)N(C)CCC1CCOCC1

InChI Key InChIKey=PINSGUVBGLYLQB-ZJWNCGCPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 549297   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741](Homo sapiens (Human))
Union Therapeutics

US Patent
LigandPNGBDBM549297(2-chloro-N- cyclobutyl-5- oxido-6,7-dihydro- thien...)
Affinity DataIC50:  30nMAssay Description:The human PDE41 Dcatalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent