BDBM549299 1-[(2-chloro-5- oxido-6,7-dihydro- thieno[3,2-d]pyrimi- din-5-ium-4- yl)amino]cyclopro- panecarbonitrile::US11299497, Example 14

SMILES CN(CCC1CCOCC1)c1nc2CC[S@@+]([O-])c2c(NC2(C)CC2)n1

InChI Key InChIKey=OXEBZZKMJHCSIO-RUZDIDTESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 549299   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741](Homo sapiens (Human))
Union Therapeutics

US Patent
LigandPNGBDBM549299(1-[(2-chloro-5- oxido-6,7-dihydro- thieno[3,2-d]py...)
Affinity DataIC50:  30nMAssay Description:The human PDE41 Dcatalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent