BDBM549717 (3R*,4R*)-1-Cyclopropylmethyl-4-{[5-(2,4,6-trifluoro-phenyl)-isoxazole-3- carbonyl]-amino}-piperidine-3-carboxylic acid ((R)-1-pyridin-2-yl-ethyl)- amide (mixture of isomers)::US11306078, Example 1.123::US11306078, Example 1.123a

SMILES C[C@@H](NC(=O)[C@@H]1CN(CC2CC2)CC[C@H]1NC(=O)c1cc(on1)-c1c(F)cc(F)cc1F)c1ccccn1

InChI Key InChIKey=YPURIRNHCNIZCS-YBOAYWMSSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 549717   

TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM549717((3R*,4R*)-1-Cyclopropylmethyl-4-{[5-(2,4,6-trifluo...)
Affinity DataIC50:  4nMAssay Description:Tango CXCR7-bla U2OS cells are detached from culture dishes with 0.05% trypsin-EDTA and collected in growing medium (McCoy's 5A 90% (v/v), dialyz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM549717((3R*,4R*)-1-Cyclopropylmethyl-4-{[5-(2,4,6-trifluo...)
Affinity DataIC50:  15nMAssay Description:Tango CXCR7-bla U2OS cells are detached from culture dishes with 0.05% trypsin-EDTA and collected in growing medium (McCoy's 5A 90% (v/v), dialyz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent