BDBM550023 5-(2,4-Difluoro-phenyl)-isoxazole-3-carboxylic acid [(3S,4S)-1- cyclopropylmethyl-3-((R)-2-phenyl-azetidine-1-carbonyl)-piperidin-4-yl]- amide::US11306078, Example 4.067b

SMILES Fc1ccc(-c2cc(no2)C(=O)N[C@@H]2CCN(CC3CC3)C[C@H]2C(=O)N2CC[C@@H]2c2ccccc2)c(F)c1

InChI Key InChIKey=GHPDLHLMIOXJKD-QIGHUWCUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 550023   

TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM550023(5-(2,4-Difluoro-phenyl)-isoxazole-3-carboxylic aci...)
Affinity DataIC50:  2nMAssay Description:Tango CXCR7-bla U2OS cells are detached from culture dishes with 0.05% trypsin-EDTA and collected in growing medium (McCoy's 5A 90% (v/v), dialyz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent