BDBM550288 2-(4-(2- ((7-(1,3- dimethyl- 1H-pyrazol- 4-yl)-[1,2,4]- triazolo[1,5- a]pyridin-2- yl)amino)-2- oxoethyl)-2- fluorophen- oxy)nicotin- amide::US11306081, Example 136

SMILES Cc1nn(C)cc1-c1ccn2nc(NC(=O)Cc3ccc(Oc4ncccc4C(N)=O)c(F)c3)nc2c1

InChI Key InChIKey=WFBKCGWFRTZMDP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 550288   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM550288(2-(4-(2- ((7-(1,3- dimethyl- 1H-pyrazol- 4-yl)-[1,...)
Affinity DataIC50:  11nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent