BDBM550786 8-(2-Methyl-6-(trifluoromethyl)pyridin-4-yl)-7-phenyl-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine 1::US11312705, Example 1

SMILES Cc1cc(cc(n1)C(F)(F)F)-c1c(nc(N)n2cnnc12)-c1ccccc1

InChI Key InChIKey=ILODIRYIWQIJFD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 550786   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM550786(8-(2-Methyl-6-(trifluoromethyl)pyridin-4-yl)-7-phe...)
Affinity DataIC50:  0.230nMAssay Description:CHO-K1/A2aR cells were cultured in DMEM/F12 medium containing 10% fetal bovine serum and 800 μg/ml bleomycin. The cells were digested with the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM550786(8-(2-Methyl-6-(trifluoromethyl)pyridin-4-yl)-7-phe...)
Affinity DataIC50:  58.5nMAssay Description:CHO-K1/A2bR cells were cultured in DMEM/F12 medium containing 10% fetal bovine serum and 1 mg/ml G418. The cells were digested with the cell separati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM550786(8-(2-Methyl-6-(trifluoromethyl)pyridin-4-yl)-7-phe...)
Affinity DataIC50:  0.230nMAssay Description:CHO-K1/A2aR cells were cultured in DMEM/F12 medium containing 10% fetal bovine serum and 800 μg/ml bleomycin. The cells were digested with the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent