BDBM550843 5-(5-Amino-7-phenyl-[1,2,4]triazolo[4,3-c]pyrimidin-8-yl)-1-isopropylpyridin-2(11-1)-one 43::US11312705, Example 43

SMILES CC(C)n1cc(ccc1=O)-c1c(nc(N)n2cnnc12)-c1ccccc1

InChI Key InChIKey=MKJJUDDAVBCRBD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 550843   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM550843(5-(5-Amino-7-phenyl-[1,2,4]triazolo[4,3-c]pyrimidi...)
Affinity DataIC50:  0.200nMAssay Description:CHO-K1/A2aR cells were cultured in DMEM/F12 medium containing 10% fetal bovine serum and 800 μg/ml bleomycin. The cells were digested with the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent