BDBM551460 (R)-9-fluoro-8-methoxy-2-(1-(1-(2,2,2-trifluoroethyl)-1H-pyrazol- 4-yl)piperidin-3-yl)[1,2,4]triazolo[1,5-c]quinazolin-5-amine::US11312719, Example 5
SMILES COc1cc2nc(N)n3nc(nc3c2cc1F)[C@@H]1CCCN(C1)c1cnn(CC(F)(F)F)c1
InChI Key InChIKey=YRBJQIQKBPRZSG-LLVKDONJSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 551460
Affinity DataIC50: 1.60nMAssay Description:The reported affinity of the compounds of the invention for the human A2b adenosine receptor was determined experimentally using a radioligand filtra...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:148 μL (5 μg/mL) membranes (Perkin Elmer, Cat. No. RBHA2aM400UA) and 2 μL compounds of the invention to be tested (test compound) were...More data for this Ligand-Target Pair