BDBM551564 1-(4-((2S,5R)-5-(5-amino-8-chloro-9-fluoro-[1,2,4]triazolo[1,5-c] quinazolin-2-yl)-2-methylpiperidin-1-yl)-1H-pyrazol-1-yl)- 2-methylpropan-2-ol::US11312719, Example 110

SMILES C[C@H]1CC[C@H](CN1c1cnn(CC(C)(C)O)c1)c1nc2c3cc(F)c(Cl)cc3nc(N)n2n1

InChI Key InChIKey=SANBAHHMAJSHHU-QWHCGFSZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 551564   

TargetAdenosine receptor A2b(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM551564(1-(4-((2S,5R)-5-(5-amino-8-chloro-9-fluoro-[1,2,4]...)
Affinity DataIC50:  1.80nMAssay Description:The reported affinity of the compounds of the invention for the human A2b adenosine receptor was determined experimentally using a radioligand filtra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM551564(1-(4-((2S,5R)-5-(5-amino-8-chloro-9-fluoro-[1,2,4]...)
Affinity DataIC50:  0.200nMAssay Description:148 μL (5 μg/mL) membranes (Perkin Elmer, Cat. No. RBHA2aM400UA) and 2 μL compounds of the invention to be tested (test compound) were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent