BDBM552594 N-[2-({4-[3-(4-fluoroanilino)-4-oxo-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-2-yl]pyridin-3-yl}oxy)ethyl]-N-methylprop-2-enamide::WO2022101184, Example 7

SMILES CN(CCOc1cnccc1-c1[nH]c2CCNC(=O)c2c1Nc1ccc(F)cc1)C(=O)C=C

InChI Key InChIKey=QGASCQZVWYACAO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552594   

TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Homo sapiens (Human))
Bayer Aktiengesellschaft

WIPO
LigandPNGBDBM552594(N-[2-({4-[3-(4-fluoroanilino)-4-oxo-4,5,6,7-tetrah...)
Affinity DataIC50:  1.62nMAssay Description: Inhibitory activity of compounds of the present invention against an Epidermal Growth Factor Receptor (EGFR) with an insertion of the amino acids se...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed