BDBM552595 (2E)-4-(dimethylamino)-N-[2-({4-[3-(3-fluoro-2-methoxyanilino)-4-oxo-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-2-yl]pyridin-3-yl}oxy)ethyl]-N-methylbut-2-enamide::WO2022101184, Example 8

SMILES COc1c(F)cccc1Nc1c([nH]c2CCNC(=O)c12)-c1ccncc1OCCN(C)C(=O)\C=C\CN(C)C

InChI Key InChIKey=WLQXZIZFNXCUCR-RMKNXTFCSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552595   

TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Homo sapiens (Human))
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WIPO
LigandPNGBDBM552595((2E)-4-(dimethylamino)-N-[2-({4-[3-(3-fluoro-2-met...)
Affinity DataIC50:  0.550nMAssay Description: Inhibitory activity of compounds of the present invention against an Epidermal Growth Factor Receptor (EGFR) with an insertion of the amino acids se...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed