BDBM552702 (2S,4R)-l-((S)-2-(4-cyclopropyl-lH-l,2,3-triazol-l-yl)-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-l-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide (Compound 18)::WO2022103411, Example S18

SMILES C[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](n1cc(nn1)C1CC1)C(C)(C)C)c1ccc(cc1)-c1scnc1C

InChI Key InChIKey=VPVWYAMEFQFVQS-HFONSACISA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552702   

Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Genentech

WIPO
LigandPNGBDBM552702((2S,4R)-l-((S)-2-(4-cyclopropyl-lH-l,2,3-triazol-l...)
Affinity DataIC50:  10nMAssay Description:The VHL NanoBRET™ Target Engagement Assay analyzes the apparent affinity of test compounds for VHL in cells by competitive displacement of a VHL Nano...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed