BDBM552707 (2S,4R)-l-((2S)-2-(adamantan-l-yl)-2-(4-cyclopropyl-lH-l,2,3-triazol-l-yl)acetyl)-N-(l-(2-chloro-4-(4-methylthiazol-5-yl)phenyl)ethyl)-4-hydroxypyrrolidine-2-carboxamide (Compound 23)::WO2022103411, Example S23

SMILES CC(NC(=O)C1C[C@@H](O)CN1C(=O)[C@H](C1C2CC3CC(C2)CC1C3)n1cc(nn1)C1CC1)c1ccc(cc1Cl)-c1scnc1C

InChI Key InChIKey=DYJLPMZYSNVISA-IILCGFKCSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552707   

Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Genentech

WIPO
LigandPNGBDBM552707((2S,4R)-l-((2S)-2-(adamantan-l-yl)-2-(4-cyclopropy...)
Affinity DataIC50:  20nMAssay Description:The VHL NanoBRET™ Target Engagement Assay analyzes the apparent affinity of test compounds for VHL in cells by competitive displacement of a VHL Nano...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed