BDBM552731 (2S, 4R)-N-((S)-l-(2'-chloro-[l,r-biphenyl]-4-yl)ethyl)-l-((S)-2-(4-cyclopropyl-lH-l,2,3-triazol-l-yl)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide ( Compound 54)::WO2022103411, Compound 54::WO2022103411, Example S46

SMILES C[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](n1cc(nn1)C1CC1)C(C)(C)C)c1ccc(cc1)-c1ccccc1Cl

InChI Key InChIKey=RQQIYJWFXPPPSS-ICTPLHBVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552731   

Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Genentech

WIPO
LigandPNGBDBM552731((2S, 4R)-N-((S)-l-(2'-chloro-[l,r-biphenyl]-4-yl)e...)
Affinity DataIC50:  10nMAssay Description:The VHL NanoBRET™ Target Engagement Assay analyzes the apparent affinity of test compounds for VHL in cells by competitive displacement of a VHL Nano...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed