BDBM552994 N-(3'-((cyclopentylamino) methyl)-6-fluoro-4-(4- methylpiperazin-1-yl)- [1,1'-biphenyl]-3-yl)-6- oxo-4-(trifluoromethyl)- 1,6-dihydropyridine-3- carboxamide::US11319299, Example 44
SMILES CN1CCN(CC1)c1cc(F)c(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cccc(CNC2CCCC2)c1
InChI Key InChIKey=MKLAJKBTIBKWMV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 552994
Affinity DataKd: 5nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
Affinity DataIC50: 1.64E+3nMAssay Description:Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...More data for this Ligand-Target Pair