BDBM554135 US11325921, Example 22

SMILES [H][C@@]12C[C@H](F)[C@@]([H])(C1)[C@H](N2)C(=O)N1CC2(C1)CN(C2)c1c(cnc2sc(CC(F)(F)F)cc12)C#N

InChI Key InChIKey=NTHBHLVHEBDGDP-YVVXQTMVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 554135   

TargetHistone-lysine N-methyltransferase 2A/Menin(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM554135(US11325921, Example 22)
Affinity DataIC50:  6.20nMAssay Description:Test for Evaluating the Inbinition of the Menin-MLL BindingMenin1-615 wherein 6× His tag and HA tag are inserted in the N-terminus, and myc tag is in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent