BDBM554139 US11325921, Example 26::US11325921, Example 27

SMILES FC(F)c1cnc2sc(CC(F)(F)F)cc2c1N1CC2(CN(C2)C(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C1

InChI Key InChIKey=JGYZPBXCLTVSLG-OZVIIMIRSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 554139   

TargetHistone-lysine N-methyltransferase 2A/Menin(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM554139(US11325921, Example 26 | US11325921, Example 27)
Affinity DataIC50:  26nMAssay Description:Test for Evaluating the Inbinition of the Menin-MLL BindingMenin1-615 wherein 6× His tag and HA tag are inserted in the N-terminus, and myc tag is in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone-lysine N-methyltransferase 2A/Menin(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM554139(US11325921, Example 26 | US11325921, Example 27)
Affinity DataIC50:  44.7nMAssay Description:Test for Evaluating the Inbinition of the Menin-MLL BindingMenin1-615 wherein 6× His tag and HA tag are inserted in the N-terminus, and myc tag is in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent