BDBM554179 US11332451, Compound I-7::US11370764, Compound I-7::US11377428, Compound I-7
SMILES CN1c2cc(CCC(=O)Nc3ccc4cn[nH]c4c3)ccc2OC[C@H](NC(=O)c2ncn(Cc3ccccc3F)n2)C1=O
InChI Key InChIKey=RJDKMPRBVKVEOC-DEOSSOPVSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 554179
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Rigel Pharmaceuticals
US Patent
Rigel Pharmaceuticals
US Patent
Affinity DataIC50: 21nMAssay Description:A 500 ml stock volume of 5× Reaction Kinase Buffer was made by mixing 1000 μl of 1M MgCl2, 500 μl of 1M Tris-HCL pH7.4, 0.5 mg/ml (25 mg) o...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Rigel Pharmaceuticals
US Patent
Rigel Pharmaceuticals
US Patent
Affinity DataIC50: 21nMAssay Description:A 500 ml stock volume of 5× Reaction Kinase Buffer was made by mixing 1000 μl of 1M MgCl2, 500 μl of 1M Tris-HCL pH7.4, 0.5 mg/ml (25 mg) o...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Rigel Pharmaceuticals
US Patent
Rigel Pharmaceuticals
US Patent
Affinity DataIC50: 21nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair