BDBM554465 US11332479, Compound 52III
SMILES Nc1cc(ccc1F)-c1nc2sccn2c1-c1ccnc(NCCCNS(=O)(=O)c2ccc(F)cc2)n1
InChI Key InChIKey=RMAWTLGYTCCDFL-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 554465
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute of Science and Technology
US Patent
Korea Institute of Science and Technology
US Patent
Affinity DataIC50: 2.68nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [696-1022,L858R](Homo sapiens (Human))
Korea Institute of Science and Technology
US Patent
Korea Institute of Science and Technology
US Patent
Affinity DataIC50: 5.41nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Korea Institute of Science and Technology
US Patent
Korea Institute of Science and Technology
US Patent
Affinity DataIC50: 1.03nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair