BDBM555264 USRE49080, Example 43

SMILES COc1ccc(cc1Cc1ccc2NC(=O)COc2c1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

InChI Key InChIKey=BXPOXWBDDUIEHX-VOFPXKNKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 555264   

TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM555264(USRE49080, Example 43)
Affinity DataIC50:  59nMAssay Description:The SGLT-2 assay is carried out as follows: CHO-hSGLT2 cells are cultivated in Ham's F12 Medium (BioWhittaker) with 10% foetal calf serum and 250...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM555264(USRE49080, Example 43)
Affinity DataIC50:  3.90nMAssay Description:The SGLT-2 assay is carried out as follows: CHO-hSGLT2 cells are cultivated in Ham's F12 Medium (BioWhittaker) with 10% foetal calf serum and 250...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent