BDBM555869 3-[2-(1-ethyl-6-fluoro-2-methyl-1,3-benzodiazol-5-yl)ethynyl]-1-[(3S,5R)-5-(methoxymethyl)-1-(Prop-2-enoyl)pyrrolidin-3-yl]-5-(methylamino)pyrazole-4-carboxamide::US11345681, Example 37

SMILES CCn1c(C)nc2cc(C#Cc3nn([C@H]4C[C@H](COC)N(C4)C(=O)C=C)c(NC)c3C(N)=O)c(F)cc12

InChI Key InChIKey=XCHKSHSGVTUCHR-ZWKOTPCHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 555869   

TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kinnate Biopharma

US Patent
LigandPNGBDBM555869(3-[2-(1-ethyl-6-fluoro-2-methyl-1,3-benzodiazol-5-...)
Affinity DataIC50: <100nMAssay Description:Small molecule inhibition of FGFR2 kinase activity was evaluated using a fluorescence-based microfluidic mobility shift assay. FGFR2 catalyzes the pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent