BDBM555876 1-[(3S,5R)-5-(methoxymethyl)-1- (prop-2-enoyl)pyrrolidin-3-yl]-3-[2-(3- methyl-1,2-benzoxazol-6-yl)ethynyl]- 5-(methylamino)pyrazole-4- carboxamide::US11345681, Example 44

SMILES CNc1c(C(N)=O)c(nn1[C@H]1C[C@H](COC)N(C1)C(=O)C=C)C#Cc1ccc2c(C)noc2c1

InChI Key InChIKey=ABHDQFMHHLWDMK-DLBZAZTESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 555876   

TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kinnate Biopharma

US Patent
LigandPNGBDBM555876(1-[(3S,5R)-5-(methoxymethyl)-1- (prop-2-enoyl)pyrr...)
Affinity DataIC50: <100nMAssay Description:Small molecule inhibition of FGFR2 kinase activity was evaluated using a fluorescence-based microfluidic mobility shift assay. FGFR2 catalyzes the pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent