BDBM556337 2-(4-(6-(5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihydro-1H-benzo[d]pyrrolo[1,2-a]imidazol-7-yl)pyrimidin-2-ylamino)pyridin-3-yloxy)piperidin-1-yl)ethanol (Compound 87)::US11351170, Example 14
SMILES CC1(C)CCc2nc3c(F)cc(cc3n12)-c1nc(Nc2ccc(OC3CCN(CCO)CC3)cn2)ncc1F
InChI Key InChIKey=WQGCPJJNZKLUAU-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 556337
Affinity DataIC50: 0.25nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Affinity DataIC50: 213nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Affinity DataIC50: 70.3nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Affinity DataIC50: 2.72nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ...More data for this Ligand-Target Pair