BDBM556399 N-(2-(dimethylamino)ethyl)-4-(2-(((1-(3-(4-(hydroxycarbamoyl)phenyl)propyl)piperidin-4-yl)methyl)amino)cyclopropyl)benzamide TFA Salt::US11352322, Compound 55

SMILES CN(C)CCNC(=O)c1ccc(cc1)C1CC1NCC1CCN(CCCc2ccc(cc2)C(=O)NO)CC1

InChI Key InChIKey=GWSJKJBRTAYFIO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 556399   

TargetHistone deacetylase 6(Homo sapiens (Human))
Jubilant Epicore

US Patent
LigandPNGBDBM556399(N-(2-(dimethylamino)ethyl)-4-(2-(((1-(3-(4-(hydrox...)
Affinity DataIC50:  130nMAssay Description:Histone deacetylase assay was done as per manufacturer's instructions. Briefly, assay buffer, 200 uM HDAC substrate (fluorogenic HDAC acetylated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Jubilant Epicore

US Patent
LigandPNGBDBM556399(N-(2-(dimethylamino)ethyl)-4-(2-(((1-(3-(4-(hydrox...)
Affinity DataIC50:  22nMAssay Description:LSD1 enzyme was produced in house. Tranylcypromine (TCP), LSD1 inhibitor was procured from Selleckchem. LSD1 enzyme, TCP and Biotinylated peptide sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent