BDBM556404 N-hydroxy-4-(3-(4-(((2-(4-(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)phenyl)cyclopropyl)amino)methyl)piperidin-1-yl)propyl)benzamide TFA Salt::US11352322, Compound 60

SMILES Cn1ccc(cc1=O)-c1ccc(cc1)C1CC1NCC1CCN(CCCc2ccc(cc2)C(=O)NO)CC1

InChI Key InChIKey=BNWKPONIDAHKBK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 556404   

TargetHistone deacetylase 6(Homo sapiens (Human))
Jubilant Epicore

US Patent
LigandPNGBDBM556404(N-hydroxy-4-(3-(4-(((2-(4-(1-methyl-2-oxo-1,2-dihy...)
Affinity DataIC50:  46nMAssay Description:Histone deacetylase assay was done as per manufacturer's instructions. Briefly, assay buffer, 200 uM HDAC substrate (fluorogenic HDAC acetylated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Jubilant Epicore

US Patent
LigandPNGBDBM556404(N-hydroxy-4-(3-(4-(((2-(4-(1-methyl-2-oxo-1,2-dihy...)
Affinity DataIC50:  21nMAssay Description:LSD1 enzyme was produced in house. Tranylcypromine (TCP), LSD1 inhibitor was procured from Selleckchem. LSD1 enzyme, TCP and Biotinylated peptide sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent