BDBM556478 2-(3-(4-(((2-(4′-fluoro-[1,1′-biphenyl]-4-yl)cyclopropyl)amino)methyl)piperidin-1-yl)propyl)-N-hydroxythiazole-4-carboxamide TFA Salt::US11352322, Compound 111
SMILES ONC(=O)c1csc(CCCN2CCC(CNC3CC3c3ccc(cc3)-c3ccc(F)cc3)CC2)n1
InChI Key InChIKey=BFGHWQXCTUHMMX-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 556478
Affinity DataIC50: 2.98E+3nMAssay Description:Histone deacetylase assay was done as per manufacturer's instructions. Briefly, assay buffer, 200 uM HDAC substrate (fluorogenic HDAC acetylated ...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:LSD1 enzyme was produced in house. Tranylcypromine (TCP), LSD1 inhibitor was procured from Selleckchem. LSD1 enzyme, TCP and Biotinylated peptide sub...More data for this Ligand-Target Pair