BDBM556509 N-(2-aminophenyl)-4-((4-((((1R,2S)-2-phenylcyclopropyl)amino)methyl)piperidin-1-yl)methyl)benzamide TFA Salt::US11352322, Compound 140

SMILES Nc1ccccc1NC(=O)c1ccc(CN2CCC(CN[C@@H]3C[C@H]3c3ccccc3)CC2)cc1

InChI Key InChIKey=OVEILBRYHDOBNP-LBNVMWSVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 556509   

TargetHistone deacetylase 6(Homo sapiens (Human))
Jubilant Epicore

US Patent
LigandPNGBDBM556509(N-(2-aminophenyl)-4-((4-((((1R,2S)-2-phenylcyclopr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Histone deacetylase assay was done as per manufacturer's instructions. Briefly, assay buffer, 200 uM HDAC substrate (fluorogenic HDAC acetylated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Jubilant Epicore

US Patent
LigandPNGBDBM556509(N-(2-aminophenyl)-4-((4-((((1R,2S)-2-phenylcyclopr...)
Affinity DataIC50:  2nMAssay Description:LSD1 enzyme was produced in house. Tranylcypromine (TCP), LSD1 inhibitor was procured from Selleckchem. LSD1 enzyme, TCP and Biotinylated peptide sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent