BDBM556511 N-(2-aminophenyl)-4-((4-(((2-(4-(1-methyl-1H-pyrazol-4-yl)phenyl)cyclopropyl)amino)methyl)piperidin-1-yl)methyl)benzamide TFA Salt::US11352322, Compound 142

SMILES Cn1cc(cn1)-c1ccc(cc1)C1CC1NCC1CCN(Cc2ccc(cc2)C(=O)Nc2ccccc2N)CC1

InChI Key InChIKey=ZTSUMSPSDNPNKE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 556511   

TargetHistone deacetylase 6(Homo sapiens (Human))
Jubilant Epicore

US Patent
LigandPNGBDBM556511(N-(2-aminophenyl)-4-((4-(((2-(4-(1-methyl-1H-pyraz...)
Affinity DataIC50: >1.00E+4nMAssay Description:Histone deacetylase assay was done as per manufacturer's instructions. Briefly, assay buffer, 200 uM HDAC substrate (fluorogenic HDAC acetylated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Jubilant Epicore

US Patent
LigandPNGBDBM556511(N-(2-aminophenyl)-4-((4-(((2-(4-(1-methyl-1H-pyraz...)
Affinity DataIC50:  12nMAssay Description:LSD1 enzyme was produced in house. Tranylcypromine (TCP), LSD1 inhibitor was procured from Selleckchem. LSD1 enzyme, TCP and Biotinylated peptide sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent