BDBM558439 N-Methyl-N-[[3-[[6-(1H-pyrazol-5-yl)-3-pyridinyl]oxymethyl]-1-bicyclo[1.1.1]pentanyl]methyl]methanesulfonamide::US11365192, Example 58-2

SMILES CN(CC12CC(COc3ccc(nc3)-c3ccn[nH]3)(C1)C2)S(C)(=O)=O

InChI Key InChIKey=ZIADXPUZMKQYCZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 558439   

TargetCytochrome P450 4A11(Homo sapiens)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM558439(N-Methyl-N-[[3-[[6-(1H-pyrazol-5-yl)-3-pyridinyl]o...)
Affinity DataIC50:  240nMAssay Description:In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 4F2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM558439(N-Methyl-N-[[3-[[6-(1H-pyrazol-5-yl)-3-pyridinyl]o...)
Affinity DataIC50:  5.10nMAssay Description:In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent