BDBM561225 6-(4-((1H- indazol-5- yl)amino)- pyrimidin-2- yl)-N-(1-(3- chloropyridin- 4-yl)piperidin- 4-yl)-1H- indole-2- carboxamide::US11390609, Compound TDI01847

SMILES Clc1cnccc1N1CCC(CC1)NC(=O)c1cc2ccc(cc2[nH]1)-c1nccc(Nc2ccc3[nH]ncc3c2)n1

InChI Key InChIKey=RANNBDKJWAWYOQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 561225   

TargetRho-associated protein kinase 2(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM561225(6-(4-((1H- indazol-5- yl)amino)- pyrimidin-2- yl)-...)
Affinity DataIC50:  14nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent