BDBM562291 4-(4-(1-(3- Fluorophenyl)-3- (methylamino)propoxy) benzyl)-1-methyl- 1,2,3,4-tetrahydro-5H- pyrido[2,3- e][1,4]diazepin-5-one::US11401270, Example 117

SMILES CNCCC(Oc1ccc(CN2CCN(C)c3ncccc3C2=O)cc1)c1cccc(F)c1

InChI Key InChIKey=CBGKKFWZEKWFKH-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 562291   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM562291(4-(4-(1-(3- Fluorophenyl)-3- (methylamino)propoxy)...)
Affinity DataKi: <100nMAssay Description:Human norepinephrine transporter (NET) enriched membranes (5 μg) were incubated with 5 nM of radiolabeled [3H]-Nisoxetin in assay buffer contain...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM562291(4-(4-(1-(3- Fluorophenyl)-3- (methylamino)propoxy)...)
Affinity DataKi:  300nMAssay Description:Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM562291(4-(4-(1-(3- Fluorophenyl)-3- (methylamino)propoxy)...)
Affinity DataKi:  300nMAssay Description:Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent