BDBM562447 2-Amino-2-[4-[[2-(5-chloro-2-thienyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]amino]phenyl]acetic acid hydrochloride::US11401286, Example 12

SMILES NC(C(O)=O)c1ccc(Nc2nc(nc3CCCc23)-c2ccc(Cl)s2)cc1

InChI Key InChIKey=HSWGOORTTHTNJZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 562447   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B [S133D](Homo sapiens (Human))
Tetra Discovery Partners

US Patent
LigandPNGBDBM562447(2-Amino-2-[4-[[2-(5-chloro-2-thienyl)-6,7-dihydro-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Assays are performed in 96-well plates in a total volume of 200 μl/well. Compounds are dissolved in dimethylsulfoxide (DMSO) and added to plates...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 7 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Tetra Discovery Partners

US Patent
LigandPNGBDBM562447(2-Amino-2-[4-[[2-(5-chloro-2-thienyl)-6,7-dihydro-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Assays are performed in 96-well plates in a total volume of 200 μl/well. Compounds are dissolved in dimethylsulfoxide (DMSO) and added to plates...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D7 [S54D](Homo sapiens (Human))
Tetra Discovery Partners

US Patent
LigandPNGBDBM562447(2-Amino-2-[4-[[2-(5-chloro-2-thienyl)-6,7-dihydro-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Assays are performed in 96-well plates in a total volume of 200 μl/well. Compounds are dissolved in dimethylsulfoxide (DMSO) and added to plates...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent