BDBM562563 2-(4-((2-(3-Hydroxycyclopentyl)-6,7-dihydro-5H-cyclopenta[b]pyridin-4-yl)amino)phenyl)acetamide: Diastereomer A::US11401286, Example 135::US11401286, Example 136::US11401286, Example 137

SMILES NC(=O)Cc1ccc(Nc2cc(nc3CCCc23)C2CCC(O)C2)cc1

InChI Key InChIKey=PLDZDPWKHIMOOL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 562563   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B [S133D](Homo sapiens (Human))
Tetra Discovery Partners

US Patent
LigandPNGBDBM562563(2-(4-((2-(3-Hydroxycyclopentyl)-6,7-dihydro-5H-cyc...)
Affinity DataIC50: >1.00E+3nMAssay Description:Assays are performed in 96-well plates in a total volume of 200 μl/well. Compounds are dissolved in dimethylsulfoxide (DMSO) and added to plates...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B [S133D](Homo sapiens (Human))
Tetra Discovery Partners

US Patent
LigandPNGBDBM562563(2-(4-((2-(3-Hydroxycyclopentyl)-6,7-dihydro-5H-cyc...)
Affinity DataIC50: >1.00E+3nMAssay Description:Assays are performed in 96-well plates in a total volume of 200 μl/well. Compounds are dissolved in dimethylsulfoxide (DMSO) and added to plates...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B [S133D](Homo sapiens (Human))
Tetra Discovery Partners

US Patent
LigandPNGBDBM562563(2-(4-((2-(3-Hydroxycyclopentyl)-6,7-dihydro-5H-cyc...)
Affinity DataIC50: >1.00E+3nMAssay Description:Assays are performed in 96-well plates in a total volume of 200 μl/well. Compounds are dissolved in dimethylsulfoxide (DMSO) and added to plates...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent