BDBM563333 US11407754, Example 7

SMILES C[C@H]1CC[C@H](CN1C(=O)C=C)Nc1nc(Nc2cnn(CC(F)F)c2)nc2[nH]cc(Cl)c12

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 563333   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Daewoong Pharmaceutical

US Patent
LigandPNGBDBM563333(US11407754, Example 7)
Affinity DataIC50:  1.60nMAssay Description:JAK3 and BTK kinases inhibitory activities were measured for the compounds prepared in the Examples through in vitro analysis on the ADP Glow (Glo) p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Daewoong Pharmaceutical

US Patent
LigandPNGBDBM563333(US11407754, Example 7)
Affinity DataIC50:  0.300nMAssay Description:JAK3 and BTK kinases inhibitory activities were measured for the compounds prepared in the Examples through in vitro analysis on the ADP Glow (Glo) p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent