BDBM563496 (2S)-2-amino-3-(4-(6- ((R)-1-(4-chloro-2-(3- methyl-1H-pyrazole-1- yl)phenyl)-2,2,2- trifluoroethoxy)-2- methylpyrimidine-4- yl)cyclohex-3-ene-1- yl)propionic acid hydrochloride::US11407763, Example 32

SMILES Cc1ccn(n1)-c1cc(Cl)ccc1[C@@H](Oc1cc(nc(C)n1)C1=CCC(C[C@H](N)C(O)=O)CC1)C(F)(F)F

InChI Key InChIKey=DZOIQWCHKOTLBE-AWYUQLRJSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 563496   

TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563496((2S)-2-amino-3-(4-(6- ((R)-1-(4-chloro-2-(3- met...)
Affinity DataIC50:  1.82E+3nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent