BDBM563851 Roche-Dataset for PDE10A, Compound 165

SMILES Cn1ncc(C(=O)N2CC(F)C2)c1C(=O)Nc1ccn2nc(nc2c1)-c1ccccc1

InChI Key InChIKey=ICNQFDNOBQVNNS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 563851   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM563851(Roche-Dataset for PDE10A, Compound 165)
Affinity DataIC50:  0.360nMAssay Description:Human PDE10A IC50 values were determined by using purified enzyme (Biomol cat. # SE-534) in a scintillation proximity assay (SPA) in 96 well plates (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed