BDBM563851 Roche-Dataset for PDE10A, Compound 165
SMILES Cn1ncc(C(=O)N2CC(F)C2)c1C(=O)Nc1ccn2nc(nc2c1)-c1ccccc1
InChI Key InChIKey=ICNQFDNOBQVNNS-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 563851
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
F. Hoffmann-La Roche
F. Hoffmann-La Roche
Affinity DataIC50: 0.360nMAssay Description:Human PDE10A IC50 values were determined by using purified enzyme (Biomol cat. # SE-534) in a scintillation proximity assay (SPA) in 96 well plates (...More data for this Ligand-Target Pair