BDBM565305 US11414416, Compound D64::US11560381, Compound D64

SMILES COc1cc(cc(OC)c1CN1CCC2(CC1)CN(CCO2)C(=O)COc1ccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c1)-c1cn(C)c(=O)c2cnccc12

InChI Key InChIKey=DUZIGRKTZUROMM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 565305   

TargetProtein SSX2/Protein SSXT(Human)
Foghorn Therapeutics

US Patent
LigandPNGBDBM565305(US11414416, Compound D64 | US11560381, Compound D6...)
Affinity DataIC50:  550nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 9 [133-239](Homo sapiens (Human))
Foghorn Therapeutics

US Patent
LigandPNGBDBM565305(US11414416, Compound D64 | US11560381, Compound D6...)
Affinity DataIC50: >10nMAssay Description:A mixture of biotinylated-ligand and SureLight Allophycocyanin-Streptavidin (APC-SA, PerkinElmer AD0201) in 50 mM HEPES (pH 7.4), 50 mM NaCl, 1 mM TC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 9 [133-239](Homo sapiens (Human))
Foghorn Therapeutics

US Patent
LigandPNGBDBM565305(US11414416, Compound D64 | US11560381, Compound D6...)
Affinity DataIC50:  55nMAssay Description:Procedure: His-Flag-BRD9 (P133-K239; Swiss Prot Q9H8M2; SEQ ID NO:1 mgsshhhhhhenlyfq/gdykddddkgslevlfqg/PAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMII...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent