BDBM5669 2-amino-5-thio-substituted thiazole 46::N-(5-{[(5-ethyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-yl)-2-methylpropanamide::N-[5-[[(5-Ethyl-2-oxazolyl)methyl]thio]-2-thiazolyl]-1-isopropylamide

SMILES CCc1cnc(CSc2cnc(NC(=O)C(C)C)s2)o1

InChI Key InChIKey=HFMGTBLBSYZDFW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 5669   

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM5669(2-amino-5-thio-substituted thiazole 46 | N-(5-{[(5...)
Affinity DataIC50:  60nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM5669(2-amino-5-thio-substituted thiazole 46 | N-(5-{[(5...)
Affinity DataIC50:  1.07E+3nMAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM5669(2-amino-5-thio-substituted thiazole 46 | N-(5-{[(5...)
Affinity DataIC50:  5nMAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed