BDBM57045 MLS000028500::NITROFURANTOIN::SMR000058271::cid_4509

SMILES [O-][N+](=O)c1ccc(\C=N\N2CC(=O)NC2=O)o1

InChI Key InChIKey=NXFQHRVNIOXGAQ-YCRREMRBSA-N

Data  1 KI  12 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 57045   

TargetCo-chaperonin GroES(Escherichia coli)
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM57045(MLS000028500 | NITROFURANTOIN | SMR000058271 | cid...)
Affinity DataIC50: >5.60E+4nMAssay Description:Inhibition of Escherichia coli GroEL/ES assessed as inhibition of native malate dehydrogenase treated after denatured malate dehydrogenase completely...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCo-chaperonin GroES(Escherichia coli)
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM57045(MLS000028500 | NITROFURANTOIN | SMR000058271 | cid...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Escherichia coli GroEL/ES-mediated refolding of the denatured malate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCo-chaperonin GroES(Escherichia coli)
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM57045(MLS000028500 | NITROFURANTOIN | SMR000058271 | cid...)
Affinity DataIC50:  8.40E+4nMAssay Description:Inhibition of Escherichia coli GroEL/ES-mediated refolding of the denatured malate dehydrogenase in presence of Escherichia coli type 1 NfsB nitrored...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCo-chaperonin GroES(Escherichia coli)
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM57045(MLS000028500 | NITROFURANTOIN | SMR000058271 | cid...)
Affinity DataIC50: >6.30E+4nMAssay Description:Inhibition of Escherichia coli GroEL/ES assessed as inhibition of native malate dehydrogenase treated after denatured malate dehydrogenase completely...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed