BDBM571422 US11440922, Example 101::ethyl (3E)-3-[3-(3- chlorophenyl)prop-2-yn-1- ylidene]-2,2- dimethylpyrrolidine-1- carboxylate
SMILES CCOC(=O)N1CC\C(=C/C#Cc2cccc(Cl)c2)C1(C)C
InChI Key InChIKey=XEMZRRSSGCTGDP-OQLLNIDSSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 571422
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati Industria Chimica E Farmacentica
US Patent
Recordati Industria Chimica E Farmacentica
US Patent
Affinity DataKi: 11.2nMAssay Description:Affinity at transmembrane glutamate metabotropic cloned human mGluR5 receptor was evaluated according to the methods of Anderson (Anderson et al., J ...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati Industria Chimica E Farmacentica
US Patent
Recordati Industria Chimica E Farmacentica
US Patent
Affinity DataIC50: 66.3nMAssay Description:Cells were seeded into black-walled, clear-bottom, 96-well plates at a density of 80000 cell/well, in RPMI (without Phenol Red, without L-glutamine; ...More data for this Ligand-Target Pair