BDBM571423 (3-chlorophenyl)[(4E)-4- {[5-(3-chlorophenyl)-1H- pyrazol-3-yl]methylidene}- 3,3-dimethylpiperidin-1- yl]methanone::US11440922, Example 107
SMILES CC1(C)CN(CC\C1=C/c1cc([nH]n1)-c1cccc(Cl)c1)C(=O)c1cccc(Cl)c1
InChI Key InChIKey=JZLIXDDNXQEUTR-QGOAFFKASA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 571423
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati Industria Chimica E Farmacentica
US Patent
Recordati Industria Chimica E Farmacentica
US Patent
Affinity DataKi: 932nMAssay Description:Affinity at transmembrane glutamate metabotropic cloned human mGluR5 receptor was evaluated according to the methods of Anderson (Anderson et al., J ...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati Industria Chimica E Farmacentica
US Patent
Recordati Industria Chimica E Farmacentica
US Patent
Affinity DataEC50: 121nMAssay Description:The PAM potency was evaluated by performing an agonist concentration response curve in the presence of the compounds. The compounds at fixed concentr...More data for this Ligand-Target Pair