BDBM576174 WO2022056448, Compound 45

SMILES OC(=O)C[C@H]1c2cnc(OCCCCCc3c(F)c(F)c(c(F)c3F)C(=O)N3CCc4ccc1cc4C3)nc2

InChI Key InChIKey=MCRMQXORHMGLQE-HXUWFJFHSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 576174   

TargetKelch-like ECH-associated protein 1/Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Sanofi

WIPO

LigandBDBM576174(WO2022056448, Compound 45)Copy SMILESCopy InChI

Affinity DataIC50:  236nMAssay Description:In a first step, the Keapl /compound complex was prepared by addition of 100 nL of the compound by ECHO 555, followed by 5 pL aliquots of 2x Keapl. T...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathway
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
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