BDBM576228 WO2022109573, Compound 19
SMILES CN1CCCCCCC(O)(c2nnc(o2)-c2nc1c(cc2N)C(F)(F)F)C(F)(F)F
InChI Key InChIKey=DBUZXPNMMFSWFF-UHFFFAOYSA-N
Data 1 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 576228
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Vertex Pharmaceuticals
WIPO
Vertex Pharmaceuticals
WIPO
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair