BDBM576233 WO2022109573, Compound 29
SMILES CC1(C)CC2CCCCCC(O)(c3nnc(o3)-c3nc(N2C1)c(cc3N)C(F)(F)F)C(F)(F)F
InChI Key InChIKey=ULQZDPGJTDNCIP-UHFFFAOYSA-N
Data 1 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 576233
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Vertex Pharmaceuticals
WIPO
Vertex Pharmaceuticals
WIPO
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair